To reset your Axiom 25, 49, and 61, hold down the + and - buttons (on the numeric keypad) simultaneously when powering up the device.

Note, resetting your Axiom in this manner will alter factory presets 6-20. (Your Axiom keyboard ships from the factory with an extended set of 20 unique presets. After resetting the device, presets 1-5 are restored and repeated over preset slots 6-10, 11-15, and 16-20. You can restore all 20 unique factory presets by using M-Audio’s free Enigma editor/librarian software.)