A: Yes. That is, balanced and/or unbalanced, stereo and/or mono. The inputs on these channels 7-14 are engineered to handle both balanced and unbalanced, and there are separate stereo [L/R] and mono inputs. All 1/4" jacks are bal/unbal and receive line level at +4 dbu or-10dbV. The difference is in units of measurement. -10 dbV (volts, where 0dbV=1 volt) results in a signal voltage of .316 (used in most consumer electronics). dbu (units, the way sound is measured), and +4 dbu result in a signal of 1.23 volts (what most pro-audio gear uses). Set the +4/-10 switch appropriately. If you want to use these as mono channels, just connect your cable to the left input only.