When you make a new bank/instrument that uses samples that already reside on your hard drive, you do not need to re-save the samples. When you save the bank and you get a dialog box asking whether you want to "Save all samples that intruments in the bank 'My New Bank' reference to a new location?" click on "Don't Save." The exception to this would be if the samples themselves have been edited using the loop editor; in this case you would want to save the changed samples.