In Pro Tools 5.3, TDM Plug-Ins on a 5.1, 6.0, 6.1 or 7.0 Master fader only...

In Pro Tools 5.3, TDM Plug-Ins on a 5.1, 6.0, 6.1 or 7.0 Master fader only pass audio through the left front channel.

This will happen only in 192k Hz sessions and only on those Master faders (5.1, 6.0, 6.1 and 7.0). All other paths work fine.
This has been fixed in Pro Tools 5.3.1

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