It is recommended that you save a different patchbay setting for each recording application. You can then just open that saved patchbay each time instead of having to completely reset the software.

Patchbay Tip 1
Always click APPLY after making any changes in the patchbay software.

Patchbay Tip 2
Always click APPLY after making any changes in the Control Panel.

Patchbay Tip 3 (Windows XP Only)
When configuring the Audio portion of the patchbay, you can hold down SHIFT and CTRL while right clicking on the first device to connect eight devices at once.