Go to [DEVICES] > [DEVICE SETUP] > [VST MULTITRACK]…for the ‘ASIO Driver’, choose “ASIO Alesis”. Close this window and go to [DEVICES] > [VST INPUTS]…drag open the window so you can see all the available inputs and click the ON button (this will turn blue when “ON”) to “Activate” selected inputs. Up to four inputs can be selected at one time (This limitation is specific to Cubase LE. Other audio applications will provide full, simultaneous access to all of the IO’s inputs and outputs).