Because the Saffire PRO 26 i/o operates in different modes depending on the sampling frequency, it may be necessary to relaunch Cubase when using the ADAT/SMUX connections. At 88.2 kHz or 96 kHz the SMUX is available. When using 44.1 kHz or 48 kHz, the ADAT connections are available. However, when switching between the two, it is necessary to relaunch Cubase for the changes in digital connections to take effect.