Yes, you will need a standard 'insert' cable, which consists of a TRS (Tip-Ring-Sleeve) connector on one end and a pair of TS (Tip-Sleeve) connectors on the other. The send from the US122 is on the tip and the receive from the effects processor is on the ring. Basically, you'll hookup the TRS side to the US122 and the pair of TS connectors to the in and out of one channel of your effects processor. You will need two cables to get stereo.