After installation, there is only one thing you need to do to get Logic Audio optimized for use with the TC PowerCore. In the "Audio" menu, select "Audio Preferences". At the bottom of the screen, make sure the "Plug-in delay compensation" box is checked (enabled) in every session where you intend to use TC PowerCore.
Also, in the "Audio Drivers" menu, it is advised to uncheck "Larger Process Buffer".

Until version 1.6 is released at the end of March, 2002, it is not advised to load a TC PowerCore Plug-in during