The DigiSystem INIT is not a multiclient driver, meaning once it's claimed by another resource, the MOTU audio system can no longer claim it. If you're getting a message like:

"Could not synchronize. Make sure that you have the same driver selected for input and output in the Sound Manager configuration dialog. (MOTU Audio System Mas SM Driver.cpp, 1336 [56:1])"

or "Error - 6011"

...when attempting to access MAS or a "no Digidesign hardware installed" message when attempting to access DAE turn the Digi sound manager driver off in the sound control panel:

1. Go to the apple menu/control panels/sound control panel.
2. For both sound in and out choose "Built-in".
3. Restart.

If the problem persists, go to the system folder/preferences folder and trash the DigiSetup file and restart. With earlier versions like DAE 2.96, the DigiSetup file is in the root of the system folder.