The PCI-324 card ships with windows MME Wave, WDM , ASIO, and GSIF support for windows 98/ME/2K/XP.

MOTU recommends wintel machines (Pentium II or III, and Celeron computers). AMD machines often ship with less efficient PCI chipsets. We've found SiS and MPV3 chipsets to be incompatible with the PCI-324 card.

There is also a known incompatibility with Pre-1999 Via Chipsets. We have been able to get recent VIA chipsets to work in some cases by downloading the "4 in 1 update" from viatech.com
One motherboard using the VIA chipset that has been working well for PCI324 users is the IWILL KK266 plus. This would be a good motherboard to use if you were building an AMD system.

If you're considering building a PC using the new DDR RAM based motherboards for use with the MOTU PCI- 324 card you may contact MOTU presales at 617-576-2760 for compatibility info.